IL12B
Some search terms matchedIL12B encodes the p40 subunit shared by IL-12 and IL-23. This makes it an intersection between immune pathways rather than a stand-alone measure of one cytokine.
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What’s searchable?IL12B encodes the p40 subunit shared by IL-12 and IL-23. This makes it an intersection between immune pathways rather than a stand-alone measure of one cytokine.
IL13 encodes interleukin-13, a cytokine involved in Th2 immune responses, mucus-related processes and tissue remodeling. It overlaps with some IL-4 functions but is not the same signal.
IL18 encodes interleukin-18, a cytokine that can promote interferon-gamma responses in the appropriate immune context. Its receptor includes components encoded by IL18R1 and IL18RAP.
IL33 encodes interleukin-33, a signal that can act as an alarmin during tissue stress and promote type 2 immune responses. It belongs in a different functional group from chemokines that recruit cells.
IL4 encodes interleukin-4, a cytokine involved in Th2 immune responses and antibody class switching, including pathways related to IgE. It operates alongside IL-5 and IL-13 rather than representing all allergic biology by itself.
TGFB1 encodes transforming growth factor beta 1, which has roles in immune regulation, tissue repair and extracellular-matrix production. Its effects can include both regulation of inflammation and promotion of fibrosis.
TNFRSF10A encodes death receptor 4, or DR4, a receptor that can receive the TRAIL signal and participate in regulated cell-death pathways. TRAIL itself is encoded by TNFSF10.
TNFSF10 encodes TRAIL, a signaling protein involved in regulated cell death through particular receptors. It is a different member of the TNF-related signaling family from TNF itself.
Refers to part of the HLA immune-recognition region, rather than one gene. HLA typing requires more detail than a broad region label.
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Explore interleukin-23 receptor, JAK2, TYK2, STAT3, and related immune signaling.
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