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This condition can cause recurring inflammation of cartilage, including the ears, nose, and sometimes the airway.

Scleritis is painful inflammation of the white outer wall of the eye and can occur with other inflammatory conditions.

This variant is in a regulatory region of the TNF gene.

This TNF promoter variant appears in Dr. Purser’s discussion of inflammatory signaling.

Primary ovarian insufficiency describes reduced ovarian function before age 40.

This inflammatory condition affects the esophagus.

This immune-mediated condition can affect the optic nerves and spinal cord.

CREST is an older name for a pattern of limited cutaneous systemic sclerosis.

Dr. Purser discusses interleukins and oxidative stress in cystic fibrosis lung disease.

Explore skin-barrier symptoms, acantholysis, cytokine networks, and redox management.

Explore rs2857261, rs1057972, natural killer cells, CD8+ T cells, and questions about high-expression variants.

Explore interleukin-1 beta, NLRP3, inflammasome activation, caspase-1, inflammatory conditions, and treatment research.