THE PURSER WELLNESS ENCYCLOPEDIA

Let’s explore “MTHFR, homocysteine, and immune signals”

Explore this topic as a step-by-step interactive map.MTHFR, the citric acid cycle & ATP
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Gene referenceSep 23, 2026

IL15RA

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…r component for IL-15. It helps present IL-15 to responding immune cells, supporting communication that is important for particular lymphocyte populations. Also called: Presenting IL-15 to responding cells IL15RA encodes the alpha receptor…

Gene referenceSep 23, 2026

IL18

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…t can promote interferon-gamma responses in the appropriate immune context. Its receptor includes components encoded by IL18R1 and IL18RAP. Also called: An inflammatory signal that connects to interferon gamma IL18 encodes interleukin-18, …

Gene referenceSep 23, 2026

IL2RA

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…interleukin-2 receptor, also called CD25. It is involved in immune activation and regulatory T-cell biology; a soluble receptor measurement is distinct from a DNA result. Also called: CD25 and immune-cell activation IL2RA encodes the alpha…

Gene referenceSep 23, 2026

IL33

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…n act as an alarmin during tissue stress and promote type 2 immune responses. It belongs in a different functional group from chemokines that recruit cells. Also called: An alarmin in allergic signaling IL33 encodes interleukin-33, a signa…

Gene referenceSep 23, 2026

IL4

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IL4 encodes interleukin-4, a cytokine involved in Th2 immune responses and antibody class switching, including pathways related to IgE. It operates alongside IL-5 and IL-13 rather than representing all allergic biology by itself. Also calle…

FacebookSep 21, 2026

MTHFR gene variants can affect how your body processes folate and methylation, key factors in overall health.

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MTHFR gene variants can affect how your body processes folate and methylation, key factors in overall health. While they don’t directly cause blood sugar crashes, understanding your genetics, nutrition, sleep, stress, and nutrient status c

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FacebookSep 15, 2026

Homocysteine rarely gets the attention of cholesterol, blood sugar, or blood pressure.

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Homocysteine rarely gets the attention of cholesterol, blood sugar, or blood pressure. It should. When homocysteine becomes elevated, it has been associated with cardiovascular disease, stroke, cognitive decline, blood clots, and other he

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FacebookAug 31, 2026

MTHFR gene variants can affect how your body processes folate and methylation, key factors in overall health.

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MTHFR gene variants can affect how your body processes folate and methylation, key factors in overall health. While they don’t directly cause blood sugar crashes, understanding your genetics, nutrition, sleep, stress, and nutrient status

YouTubeAug 29, 2026

MTHFR and the Never-Ending Sugar Crash Cycle: Why You’re Tired, Craving Sugar, and Chasing Energy A

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That afternoon sugar craving may be telling you more than you think. Here’s how methylation, glucose, cellular energy and your genetics may fit into the bigger picture. https://danpursermd.substack.com/p/mthfr-and-the-never-ending-sugar?utm_source=youtube

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FacebookAug 22, 2026

Certain genetic variants can affect MTHFR enzyme activity, which is why understanding your individual biology can…

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Certain genetic variants can affect MTHFR enzyme activity, which is why understanding your individual biology can change the conversation around nutrition. That is where MTHFR Daily comes in. Designed with methylation support in mind, MTH

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