B vitamins and bone health
Explore folate, B12, B6, and homocysteine in a bone-health discussion.
THE PURSER WELLNESS ENCYCLOPEDIA
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A RELATED COURSEYour MTHFR starting point
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47 resources
What’s searchable?Homocysteine, folate transport, and uric acid
Explore Dr. Purser’s connection between methylation and purine pathways.
MTHFR, homocysteine, and immune signals
Follow Dr. Purser’s discussion of folate metabolism and inflammation.
TNF rs1800629
This variant is in a regulatory region of the TNF gene.
TNF rs1799724
This TNF promoter variant appears in Dr. Purser’s discussion of inflammatory signaling.
Primary ovarian insufficiency and immune signals
Primary ovarian insufficiency describes reduced ovarian function before age 40.
G6PC2 and fasting glucose
G6PC2 participates in glucose handling in pancreatic beta cells.
DAOA / G72 (rs2391191)
Explore D-amino acid oxidase activator (DAOA / G72), rs2391191, D-serine, NMDA receptors, glutamate signaling, and research questions about brain and mood.
Vitamin B9 / folate deficiency
Explore folate, vitamin B9, one-carbon metabolism, anemia, homocysteine, SLC19A1, and differences between folate forms and transport pathways.
HFE (H63D / rs1799945) & iron
Explore HFE, H63D, rs1799945, C282Y, hereditary hemochromatosis, iron overload, ferritin, transferrin saturation, and monitoring and phlebotomy.
Hirschsprung’s disease & genetics
Explore enteric nerve development, aganglionosis, bowel function, RET, EDNRB, EDN3, SOX10, PHOX2B, and genetic syndromes discussed alongside Hirschsprung’s disease.
IL-15 & homozygosity
Explore rs2857261, rs1057972, natural killer cells, CD8+ T cells, and questions about high-expression variants.
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